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TGF beta-induced growth inhibition in primary fibroblasts requires the retinoblastoma protein.
Transforming growth factor beta (TGF beta) inhibits cell proliferation by inducing a G1 cell-cycle arrest. Cyclin/CDK complexes have been implicated in this arrest, because TGF beta treatment leads to inhibition of cyclin/CDK activity. We have investigated the role of the retinoblastoma protein (pRb...
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| Publicado en: | Mol Biol Cell |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Cell Biology
1996
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275985/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8885230/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.7.9.1335 |
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