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Enzyme Activity of Phosphatase of Regenerating Liver (PRL-1) Is Controlled by Redox Environment and Its C-terminal Residues

Phosphatase of regenerating liver-1 (PRL-1) belongs to a unique subfamily of protein tyrosine phosphatases (PTPases) associated with oncogenic and metastatic phenotypes. While considerable evidence exists to supports a role for PRL-1 in promoting proliferation, the biological regulators and effector...

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Detalhes bibliográficos
Main Authors: Skinner, Andria L., Vartia, Anthony A., Williams, Todd D., Laurence, Jennifer S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759777/
https://ncbi.nlm.nih.gov/pubmed/19341304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900241k
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