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Influenza A Gradual and Epochal Evolution: Insights from Simple Models

The recurrence of influenza A epidemics has originally been explained by a “continuous antigenic drift” scenario. Recently, it has been shown that if genetic drift is gradual, the evolution of influenza A main antigen, the haemagglutinin, is punctuated. As a consequence, it has been suggested that i...

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Detalhes bibliográficos
Main Authors: Ballesteros, Sébastien, Vergu, Elisabeta, Cazelles, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759541/
https://ncbi.nlm.nih.gov/pubmed/19841740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007426
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