Selection of Inhibitor-Resistant Viral Potassium Channels Identifies a Selectivity Filter Site that Affects Barium and Amantadine Block

BACKGROUND: Understanding the interactions between ion channels and blockers remains an important goal that has implications for delineating the basic mechanisms of ion channel function and for the discovery and development of ion channel directed drugs. METHODOLOGY/PRINCIPAL FINDINGS: We used genet...

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Bibliografische gegevens
Hoofdauteurs: Chatelain, Franck C., Gazzarrini, Sabrina, Fujiwara, Yuichiro, Arrigoni, Cristina, Domigan, Courtney, Ferrara, Giuseppina, Pantoja, Carlos, Thiel, Gerhard, Moroni, Anna, Minor, Daniel L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2009
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759520/
https://ncbi.nlm.nih.gov/pubmed/19834614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007496
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