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Characterization of a chimeric monoclonal antibody against the insulin-like growth factor-I receptor

The insulin-like growth factors (IGFs) signaling system has been shown to play important roles in neoplasia. The IGF receptor type 1 (IGF-IR) is overexpressed in many types of solid and hematopoietic malignancies, and there is substantial experimental and clinical evidence that targeting IGF-IR is a...

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Detalhes bibliográficos
Main Authors: Zhang, Mei-Yun, Feng, Yang, Wang, Yanping, Dimitrov, Dimiter S
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759497/
https://ncbi.nlm.nih.gov/pubmed/20065647
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