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Myocardial ischemic postconditioning against ischemia-reperfusion is impaired in ob/ob mice

Ischemic postconditioning (IPCD) significantly reduces infarct size in healthy animals and protects the human heart. Because obesity is a major risk factor of cardiovascular diseases, the effects of IPCD were investigated in 8–10 weeks old leptin-deficient obese mice (ob/ob) and compared to wild-typ...

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Detalhes bibliográficos
Main Authors: Bouhidel, Omar, Pons, Sandrine, Souktani, Richard, Zini, Roland, Berdeaux, Alain, Ghaleh, Bijan
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759460/
https://ncbi.nlm.nih.gov/pubmed/18689499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00379.2008
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