Inhibition of cAMP Responsive Element Binding Protein in Striatal Neurons Enhances Approach and Avoidance Responses toward Morphine- and Morphine Withdrawal-related Cues

To investigate the role of cAMP responsive element binding protein (CREB)-dependent gene expression in morphine induced behaviors, we examined bitransgenic mice expressing a dominant and strong inhibitor of the CREB family of transcription factors, A-CREB, in striatal neurons in a regulatable manner...

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Detalhes bibliográficos
Main Authors: Sanchis-Segura, Carles, Jancic, Dragana, Jimenez-Minchan, Maria, Barco, Angel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2009
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759365/
https://ncbi.nlm.nih.gov/pubmed/19826619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/neuro.08.030.2009
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