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High-Throughput Phase-Distribution Method to Determine Drug-Cyclodextrin Binding Constants
A high-throughput method has been developed to measure drug-cyclodextrin binding constants. It measures the distribution ratio of a drug between a polymer film [polyvinyl chloride (PVC) with 67% (w/w) dioctyl sebacate (DOS)] and a cyclodextrin-containing buffer in a 96-well format. Measurements of d...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2759112/ https://ncbi.nlm.nih.gov/pubmed/18428984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.21396 |
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