Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeast.

pep12/vps6 mutants of Saccharomyces cerevisiae are defective in delivery of soluble vacuolar hydrolases to the vacuole. Morphological analysis by electron microscopy revealed that pep12 cells accumulate 40- to 50-nm vesicles. Furthermore, pep12 cells have enlarged vacuoles characteristic of class D...

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Pubblicato in:	Mol Biol Cell
Autori principali:	Becherer, K A, Rieder, S E, Emr, S D, Jones, E W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Cell Biology 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275911/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8730101/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.7.4.579
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