Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis

Leukotrienes are arachidonic acid derivatives long known for their inflammatory properties and their involvement with a number of human diseases, most particularly asthma. Recently, leukotriene-based inflammation has also been shown to play an important role in atherosclerosis: ALOX5AP and LTA4H, bo...

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Auteurs principaux: Crosslin, David R., Shah, Svati H., Nelson, Sarah C., Haynes, Carol S., Connelly, Jessica J., Gadson, Shera, Goldschmidt-Clermont, Pascal J., Vance, Jeffery M., Rose, Jason, Granger, Chris B., Seo, David, Gregory, Simon G., Kraus, William E., Hauser, Elizabeth R.
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759090/
https://ncbi.nlm.nih.gov/pubmed/19130089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-008-0619-0
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