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Direct Repeat 6 from Human Herpesvirus-6B Encodes a Nuclear Protein that Forms a Complex with the Viral DNA Processivity Factor p41

The SalI-L fragment from human herpesvirus 6A (HHV-6A) encodes a protein DR7 that has been reported to produce fibrosarcomas when injected into nude mice, to transform NIH3T3 cells, and to interact with and inhibit the function of p53. The homologous gene in HHV-6B is dr6. Since p53 is deregulated i...

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Detalhes bibliográficos
Main Authors: Schleimann, Mariane H., Møller, Janni M. L., Kofod-Olsen, Emil, Höllsberg, Per
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759074/
https://ncbi.nlm.nih.gov/pubmed/19829698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007457
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