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Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on α3β1 integrin

Recent studies have shown that galectin-3 (Gal-3; also known as LGALS3), a β-galactoside-binding lectin, promotes cell migration during re-epithelialization of corneal wounds. The goal of this study was to characterize the molecular mechanism by which Gal-3 stimulates cell migration. We demonstrate...

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Autors principals: Saravanan, Chandrassegar, Liu, Fu-Tong, Gipson, Ilene K., Panjwani, Noorjahan
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758802/
https://ncbi.nlm.nih.gov/pubmed/19755493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.045674
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