A Mediator of Rho-dependent Invasion Moonlights as a Methionine Salvage Enzyme

RhoA controls changes in cell morphology and invasion associated with cancer phenotypes. Cell lines derived from melanoma tumors at varying stages revealed that RhoA is selectively activated in cells of metastatic origin. We describe a functional proteomics strategy to identify proteins regulated by...

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Detalhes bibliográficos
Main Authors: Kabuyama, Yukihito, Litman, Elizabeth S., Templeton, Paul D., Metzner, Sandra I., Witze, Eric S., Argast, Gretchen M., Langer, Stephen J., Polvinen, Kirsi, Shellman, Yiqun, Chan, Daniel, Shabb, John B., Fitzpatrick, James E., Resing, Katheryn A., Sousa, Marcelo C., Ahn, Natalie G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758758/
https://ncbi.nlm.nih.gov/pubmed/19620624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900178-MCP200
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