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Long-range spreading of dosage compensation in Drosophila captures transcribed autosomal genes inserted on X

Dosage compensation in Drosophila melanogaster males is achieved via targeting of male-specific lethal (MSL) complex to X-linked genes. This is proposed to involve sequence-specific recognition of the X at ∼150–300 chromatin entry sites, and subsequent spreading to active genes. Here we ask whether...

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Detalles Bibliográficos
Autores principales: Gorchakov, Andrey A., Alekseyenko, Artyom A., Kharchenko, Peter, Park, Peter J., Kuroda, Mitzi I.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758747/
https://ncbi.nlm.nih.gov/pubmed/19797766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1840409
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