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Simvastatin and Atorvastatin Improve Neurological Outcome after Experimental Intracerebral Hemorrhage

BACKGROUND AND PURPOSE: This study investigates the effects of statin treatment on experimental intracerebral hemorrhage (ICH) using behavioral, histological, and magnetic resonance imaging (MRI) measures of recovery. METHODS: Primary ICH was induced in rats. Simvastatin (2 mg/kg), atorvastatin (2 m...

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Bibliographic Details
Main Authors: Karki, Kishor, Knight, Robert A., Han, Yuxia, Yang, Dongmei, Jianfeng, Zhang, Ledbetter, Karyn A., Chopp, Michael, Seyfried, Donald M.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758425/
https://ncbi.nlm.nih.gov/pubmed/19644071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.108.544395
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