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Study of the Cis to Trans Isomerization of 1-Phenyl-2,3-disubstituted Tetrahydro-β-carbolines at C(1). Evidence for the Carbocation-Mediated Mechanism

[Image: see text] The present study was undertaken to shed light on the mechanism of the epimerization of cis-1,2,3-trisubstituted tetrahydro-β-carbolines into the trans isomers via a potential carbocationic intermediate at C(1). In order to study the pathway involved in C(1)–N(2) bond cleavage, the...

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Detalhes bibliográficos
Main Authors: Kumpaty, Hephzibah J., Van Linn, Michael L., Kabir, M. Shahjahan, Försterling, F. Holger, Deschamps, Jeffrey R., Cook, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758420/
https://ncbi.nlm.nih.gov/pubmed/19275130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo8028168
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