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Population Pharmacodynamic Parameter Estimation from Sparse Sampling: Effect of Sigmoidicity on Parameter Estimates

The objective of this stimulation study was to evaluate effect of simoidicity of the concentration–effect (C–E) relationship on the efficiency of population parameter estimation from sparse sampling and is a continuation of previous work that addressed the effect of sample size and number of samples...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pai, Sudhakar M., Girgis, Suzette, Batra, Vijay K., Girgis, Ihab G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758124/
https://ncbi.nlm.nih.gov/pubmed/19629711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9131-2
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