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The untapped potential of genetically-engineered mouse models in chemoprevention research: Opportunities and challenges

The past decade has witnessed the unveiling of a powerful new generation of genetically-engineered mouse (GEM) models of human cancer, which are proving to be highly effective for elucidating cancer mechanisms and interrogating novel experimental therapeutics. This new generation of GEM models are w...

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Detalhes bibliográficos
Main Authors: Abate-Shen, Cory, Brown, Powel H., Colburn, Nancy H., Gerner, Eugene W., Green, Jeffery E., Lipkin, Martin, Nelson, William G., Threadgill, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758098/
https://ncbi.nlm.nih.gov/pubmed/19138951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-08-0076
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