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TSLP and IL-7 use two different mechanisms to regulate human CD4(+) T cell homeostasis

Whether thymic stromal lymphopoietin (TSLP) directly induces potent human CD4(+) T cell proliferation and Th2 differentiation is unknown. We report that resting and activated CD4(+) T cells expressed high levels of IL-7 receptor a chain but very low levels of TSLP receptor (TSLPR) when compared with...

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Autori principali: Lu, Ning, Wang, Yi-Hong, Wang, Yui-Hsi, Arima, Kazuhiko, Hanabuchi, Shino, Liu, Yong-Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757885/
https://ncbi.nlm.nih.gov/pubmed/19770269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090153
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