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Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease

Expression of enzymatically inactive caspase-8, or deletion of caspase-8 from basal epidermal keratinocytes, triggers chronic skin inflammation in mice. Unlike similar inflammation resulting from arrest of nuclear factor κB activation in the epidermal cells, the effect induced by caspase-8 deficienc...

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Hlavní autoři: Kovalenko, Andrew, Kim, Jin-Chul, Kang, Tae-Bong, Rajput, Akhil, Bogdanov, Konstantin, Dittrich-Breiholz, Oliver, Kracht, Michael, Brenner, Ori, Wallach, David
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757876/
https://ncbi.nlm.nih.gov/pubmed/19720838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090616
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