Protective Effects of PARP-1 Knockout on Dyslipidemia-Induced Autonomic and Vascular Dysfunction in ApoE(−/−) Mice: Effects on eNOS and Oxidative Stress

The aims of this study were to investigate the role of poly(ADP-ribose) polymerase (PARP)-1 in dyslipidemia-associated vascular dysfunction as well as autonomic nervous system dysregulation. Apolipoprotein (ApoE)(−/−) mice fed a high-fat diet were used as a model of atherosclerosis. Vascular and aut...

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Detalhes bibliográficos
Main Authors: Hans, Chetan P., Feng, Yumei, Naura, Amarjit S., Zerfaoui, Mourad, Rezk, Bashir M., Xia, Huijing, Kaye, Alan D., Matrougui, Khalid, Lazartigues, Eric, Boulares, A. Hamid
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757717/
https://ncbi.nlm.nih.gov/pubmed/19823587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007430
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