Elimination of cdc2 phosphorylation sites in the cdc25 phosphatase blocks initiation of M-phase.
The cdc25 phosphatase is a mitotic inducer that activates p34cdc2 at the G2/M transition by dephosphorylation of Tyr15 in p34cdc2. cdc25 itself is also regulated through periodic changes in its phosphorylation state. To elucidate the mechanism for induction of mitosis, phosphorylation of cdc25 has b...
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| Publicado en: | Mol Biol Cell |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Cell Biology
1993
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275769/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7513216/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.4.12.1337 |
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