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The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF.

Vascular endothelial growth factor (VEGF)mRNA undergoes alternative splicing events that generate four different homodimeric isoforms, VEGF121, VEGF165, VEGF189, or VEGF206. VEGF121 is a nonheparin-binding acidic protein, which is freely diffusible. The longer forms, VEGF189 or VEGF206, are highly b...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Park, J E, Keller, G A, Ferrara, N
Format: Artigo
Language:Inglês
Published: American Society for Cell Biology 1993
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275767/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8167412/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.4.12.1317
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