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Isotopomer analysis of lipid biosynthesis by high resolution mass spectrometry and NMR

We have coupled 2D-NMR and infusion FT-ICR-MS with computer-assisted assignment to profile (13)C-isotopologues of glycerophospholipids (GPL) directly in crude cell extracts, resulting in very high information throughput of >3000 isobaric molecules in a few minutes. A mass accuracy of better than...

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Autores principales: Lane, Andrew N., Fan, Teresa W-M., Xie, Zhengzhi, Moseley, Hunter N.B., Higashi, Richard M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757635/
https://ncbi.nlm.nih.gov/pubmed/19782812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aca.2009.08.032
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