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Towards extracellular Ca(2+) sensing by MRI: synthesis and calcium-dependent (1)H and (17)O relaxation studies of two novel bismacrocyclic Gd(3+) complexes
Two new bismacrocyclic Gd(3+) chelates containing a specific Ca(2+) binding site were synthesized as potential MRI contrast agents for the detection of Ca(2+) concentration changes at the millimolar level in the extracellular space. In the ligands, the Ca(2+)-sensitive BAPTA-bisamide central part is...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757613/ https://ncbi.nlm.nih.gov/pubmed/17874148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-007-0296-9 |
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