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Thyroid peroxidase forms thionamide-sensitive homodimers: relevance for immunomodulation of thyroid autoimmunity
Thyroid peroxidase (TPO) is the key enzyme in thyroid hormone production and a universal autoantigen in Graves’ and other autoimmune thyroid diseases. We wished to explore the expression of TPO and whether it was affected by thionamide antithyroid drugs. We studied recombinant TPO, stably expressed...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
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Springer-Verlag
2009
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757584/ https://ncbi.nlm.nih.gov/pubmed/19669106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-009-0511-y |
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