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Role of Neurotrophin Receptor TrkB in the Maturation of Rod Photoreceptors and Establishment of Synaptic Transmission to the Inner Retina

Brain-derived neurotrophic factor (BDNF) acts through TrkB, a receptor with kinase activity, and mitigates light-induced apoptosis in adult mouse rod photoreceptors. To determine whether TrkB signaling is necessary for rod development and function, we examined the retinas of mice lacking all isoform...

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Autori principali: Rohrer, Baerbel, Korenbrot, Juan I., LaVail, Matthew M., Reichardt, Louis F., Xu, Baoji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757409/
https://ncbi.nlm.nih.gov/pubmed/10516311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-20-08919.1999
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