Suppression of yeast geranylgeranyl transferase I defect by alternative prenylation of two target GTPases, Rho1p and Cdc42p.

Geranylgeranyl transferase I (GGTase I), which modifies proteins containing the sequence Cys-Ali-Ali-Leu (Ali: aliphatic) at their C-termini, is indispensable for growth in the budding yeast Saccharomyces cerevisiae. We report here that GGTase I is no longer essential when Rho1p and Cdc42p are simul...

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Publié dans:	Mol Biol Cell
Auteurs principaux:	Ohya, Y, Qadota, H, Anraku, Y, Pringle, J R, Botstein, D
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Cell Biology 1993
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275735/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8298188/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.4.10.1017
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