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Nuclear Export-independent Inhibition of Foxa2 by Insulin

The Forkhead box A2 transcription factor (Foxa2/HNF-3β) has been shown to be a key regulator of genes involved in the maintenance of glucose and lipid homeostasis in the liver. It is constitutively inactivated in several hyperinsulinemic/obese mouse models, thereby enhancing their metabolic phenotyp...

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Autores principales: Howell, Jessica J., Stoffel, Markus
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757185/
https://ncbi.nlm.nih.gov/pubmed/19589781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.042135
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