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Long antisense non-coding RNAs function to direct epigenetic complexes that regulate transcription in human cells

Epigenetic silencing of tumor suppressor gene promoters is one of the most common observations found in cancer. Despite the plethora of observed epigenetically silenced cancer related genes little is known about what is guiding the silencing to these particular loci. Two recent articles suggest that...

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Detalhes bibliográficos
Autor principal: Morris, Kevin V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757163/
https://ncbi.nlm.nih.gov/pubmed/19633414
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