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Increased manganese superoxide dismutase expression or treatment with a manganese porphyrin potentiates dexamethasone-induced apoptosis in lymphoma cells

Glucocorticoid-induced apoptosis is exploited for the treatment of hematologic malignancies. Innate and acquired resistance limits treatment efficacy; however, resistance mechanisms are not well understood. Previously, using WEHI7.2 murine thymic lymphoma cells, we found that increasing the resistan...

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Detalhes bibliográficos
Main Authors: Jaramillo, Melba C., Frye, Jennifer B., Crapo, James D., Briehl, Margaret M., Tome, Margaret E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757156/
https://ncbi.nlm.nih.gov/pubmed/19549914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4031
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