Development of a platelet-activating factor antagonist for HIV-1 associated neurocognitive disorders

The neuroregulatory activities of PMS-601, a platelet activating factor antagonist, were investigated in laboratory and animal models of HIV-1 encephalitis (HIVE). For the former, PMS-601 reduced monocyte-derived macrophage pro-inflammatory factors, multinucleated giant cell (MGC) formation, and neu...

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Autori principali: Eggert, Dawn, Dash, Prasanta K., Serradji, Nawal, Dong, Chang-Zhi, Clayette, Pascal, Heymans, Francoise, Dou, Huanyu, Gorantla, Santhi, Gelbard, Harris A., Poluektova, Larisa, Gendelman, Howard E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757154/
https://ncbi.nlm.nih.gov/pubmed/19541372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2009.06.002
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