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Successful interstitial navigation by killer T cells enables efficient anti-tumor immunity

A killer T lymphocyte must both seek and destroy transformed cells within cancerous tissue in order to eliminate a tumor. Although lymphocytes are constitutively non-adherent cells, they undergo facultative polarity during migration and upon interaction with cells presenting cognate antigen, suggest...

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Detalhes bibliográficos
Main Authors: Mrass, Paulus, Kinjyo, Ichiko, Ng, Lai Guan, Reiner, Steven L., Puré, Ellen, Weninger, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757129/
https://ncbi.nlm.nih.gov/pubmed/19100702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.10.015
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