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Androgen Increases AT1a Receptor Expression in Abdominal Aortas to Promote Angiotensin II-Induced AAAs in Apolipoprotein E Deficient Mice

OBJECTIVE: Castration of male apolipoprotein E deficient (apoE-/-) mice reduces angiotensin II (AngII)-induced abdominal aorta aneurysms (AAAs) to that of female mice. The purpose of this study was to determine whether this reduction is due to androgen-mediated regulation of aortic AngII type 1A rec...

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Bibliografische gegevens
Hoofdauteurs: Henriques, Tracy, Zhang, Xuan, Yiannikouris, Frederique B., Daugherty, Alan, Cassis, Lisa A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757112/
https://ncbi.nlm.nih.gov/pubmed/18451329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.107.160382
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