Llwytho...

Sequestration of essential proteins causes prion associated toxicity in yeast

Prions are infectious, aggregated proteins that cause diseases in mammals but are not normally toxic in fungi. Excess Sup35p, an essential yeast protein that can exist as the [PSI(+)] prion, inhibits growth of [PSI(+)] but not [psi(−)] cells. This toxicity is rescued by expressing the Sup35Cp domain...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vishveshwara, Namitha, Bradley, Michael E., Liebman, Susan W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757070/
https://ncbi.nlm.nih.gov/pubmed/19682262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2009.06836.x
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