In vitro and in vivo analysis of [(64)Cu-NO2A-8-Aoc-BBN(7–14)NH(2)]: a site-directed radiopharmaceutical for positron-emission tomography imaging of T-47D human breast cancer tumors

INTRODUCTION: Human breast cancer, from which the T-47D cell line was derived, is known to overexpress the gastrin-releasing peptide receptor (GRPR) in some cases. Bombesin (BBN), an agonist for the GRPR, has been appended with a radionuclide capable of positron-emission tomography (PET) imaging and...

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Hauptverfasser: Prasanphanich, Adam F., Retzloff, Lauren, Lane, Stephanie R., Nanda, Prasant K., Sieckman, Gary L., Rold, Tammy L., Ma, Lixin, Figueroa, Said D., Sublett, Samantha V., Hoffman, Timothy J., Smith, Charles J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756974/
https://ncbi.nlm.nih.gov/pubmed/19217529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2008.11.005
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