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Toll-Like Receptor 3 Ligand and Retinoic Acid Enhance Germinal Center Formation and Increase the Tetanus Toxoid Vaccine Response

Immunizations with T-cell-dependent antigens induce the formation of germinal centers (GC), unique lymphoid microenvironments in which antigen-activated B cells undergo class switching, affinity maturation, and differentiation into memory B cells. Poly(I:C) (PIC), a double-stranded RNA, and retinoic...

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Detalhes bibliográficos
Main Authors: Ma, Yifan, Ross, A. Catharine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756847/
https://ncbi.nlm.nih.gov/pubmed/19692622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00282-09
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