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Uremic levels of urea inhibit l-arginine transport in cultured endothelial cells

Hypertension in end-stage renal disease (ESRD) may involve lack of endothelial nitric oxide (NO), as suggested by reduced total NO synthase (NOS) in dialysis patients. One reason might be due to substrate deficiency. To test the hypothesis that uremia is a state of intracellular l-arginine deficienc...

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Detalhes bibliográficos
Main Authors: XIAO, SHEN, WAGNER, LASZLO, MAHANEY, JAMES, BAYLIS, CHRIS
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756804/
https://ncbi.nlm.nih.gov/pubmed/11352838
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