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Uremic levels of urea inhibit l-arginine transport in cultured endothelial cells

Hypertension in end-stage renal disease (ESRD) may involve lack of endothelial nitric oxide (NO), as suggested by reduced total NO synthase (NOS) in dialysis patients. One reason might be due to substrate deficiency. To test the hypothesis that uremia is a state of intracellular l-arginine deficienc...

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Hlavní autoři: XIAO, SHEN, WAGNER, LASZLO, MAHANEY, JAMES, BAYLIS, CHRIS
Médium: Artigo
Jazyk:Inglês
Vydáno: 2001
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756804/
https://ncbi.nlm.nih.gov/pubmed/11352838
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