The Potential Functional Interaction of Biglycan and WISP-1 in Controlling Differentiation and Proliferation of Osteogenic Cells

Biglycan (BGN) and WISP-1 are 2 extracellular matrix proteins that bind to each other and colocalize in mineralizing tissue. Here we show that WISP-1 abrogates the repression of proliferation in bone marrow stromal cells induced by BGN. We also demonstrate that WISP-1 and its variant WISP-1va can al...

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Main Authors: Inkson, Colette A., Ono, Mitsuaki, Bi, Yanming, Kuznetsov, Sergei A., Fisher, Larry W., Young, Marian F.
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756790/
https://ncbi.nlm.nih.gov/pubmed/18701807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000151377
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