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Use of nuclear magnetic resonance-based metabolomics in detecting drug resistance in cancer

Cancer cells possess a highly unique metabolic phenotype, which is characterized by high glucose uptake, increased glycolytic activity, decreased mitochondrial activity, low bioenergetic and increased phospholipid turnover. These metabolic hallmarks can be readily assessed by metabolic technologies...

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Detalhes bibliográficos
Main Authors: Merz, Andrea L, Serkova, Natalie J
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756767/
https://ncbi.nlm.nih.gov/pubmed/20160999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/BMM.09.15
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