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Aldo-Keto Reductase Family 1 B10 Protein Detoxifies Dietary and Lipid-Derived Alpha, Beta-Unsaturated Carbonyls at Physiological Levels

Alpha, beta-unsaturated carbonyls are highly reactive mutagens and carcinogens to which humans are exposed on a daily basis. This study demonstrates that aldo-keto reductase family 1 member B10 (AKR1B10) is a critical protein in detoxifying dietary and lipid-derived unsaturated carbonyls. Purified A...

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Detalhes bibliográficos
Main Authors: Zhong, Linlin, Liu, Ziwen, Yan, Ruilan, Johnson, Stephen, Fang, Xiubin, Cao, Deliang
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756731/
https://ncbi.nlm.nih.gov/pubmed/19563777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.06.123
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