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Secreted Frizzled Related Protein 1 is a Target to Improve Fracture Healing

Genetic studies have identified a high bone mass of phenotype in both human and mouse when canonical Wnt signaling is increased. Secreted frizzled related protein1 (sFRP1) is one of several Wnt antagonists and among the loss-of-function mouse models in which 32-week old mice exhibit a high bone mass...

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Autori principali: Gaur, Tripti, Wixted, John J., Hussain, Sadiq, O’Connell, Shannon, Morgan, Elise F., Ayers, David, Komm, Barry S., Bodine, Peter V., Stein, Gary S., Lian, Jane B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756719/
https://ncbi.nlm.nih.gov/pubmed/19301255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21747
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