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No association between a TPH2 promoter polymorphism and mood disorders or monoamine turnover

BACKGROUND: Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in serotonin synthesis. TPH2 is a recently discovered isoform that is expressed predominantly in serotonin neurons. Associations are reported of TPH2 polymorphisms with MDD, bipolar disorder and suicidal behavior. This study examin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mann, J. John, Currier, Dianne, Murphy, Lauren, Huang, Yung-yu, Galfalvy, Hanga, Brent, David, Greenhill, Laurence, Oquendo, Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756663/
https://ncbi.nlm.nih.gov/pubmed/17604842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jad.2007.05.031
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