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Signal transduction by the platelet integrin alpha IIb beta 3: induction of calcium oscillations required for protein-tyrosine phosphorylation and ligand-induced spreading of stably transfected cells.

We demonstrate an example of signal transduction by an integrin and have begun to define the pathway through which this signaling is achieved. We constructed a stably transfected derivative of 293 cells (ATCC 1573) that expresses the platelet integrin GPIIbIIIa (alpha IIb beta 3). This cell line, cl...

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Detalles Bibliográficos
Publicado en:Mol Biol Cell
Autores principales: Pelletier, A J, Bodary, S C, Levinson, A D
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Cell Biology 1992
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275660/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1421580/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.3.9.989
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