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A critical role of eEF-2K in mediating autophagy in response to multiple cellular stresses

The phosphorylation of the subunit α of eukaryotic translation initiation factor 2 (eIF2α), a critical regulatory event in controlling protein translation, has recently been found to mediate the induction of autophagy. However, the mediators of autophagy downstream of eIF2α remain unknown. Here, we...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Py, Bénédicte F., Boyce, Michael, Yuan, Junying
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756538/
https://ncbi.nlm.nih.gov/pubmed/19221463
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