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Studies Toward the Synthesis of Spirolides: Assembly of the Elaborated E-Ring Fragment
A stereoselective synthesis of the spiroimine fragment of spirolide C is described. The congested C7 and C29 tertiary and quaternary centers are constructed by a diastereoselective Ireland-Claisen rearrangement. The E ring is completed by means of an aldol cyclocondensation. Additional studies were...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756537/ https://ncbi.nlm.nih.gov/pubmed/19199776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol8027797 |
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