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Periodic changes in phosphorylation of the Xenopus cdc25 phosphatase regulate its activity.

The cdc25 tyrosine phosphatase is known to activate cdc2 kinase in the G2/M transition by dephosphorylation of tyrosine 15. To determine how entry into M-phase in eukaryotic cells is controlled, we have investigated the regulation of the cdc25 protein in Xenopus eggs and oocytes. Two closely related...

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Publicado en:Mol Biol Cell
Autores principales: Izumi, T, Walker, D H, Maller, J L
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Cell Biology 1992
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275649/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1392080/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.3.8.927
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