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Is TEA an inhibitor for human Aquaporin-1?

Excessive water uptake through aquaporins can be life threatening, and disregulation of water permeability causes many diseases. Therefore, reversible aquaporin inhibitors are highly desired. In this paper, we identified the binding site for tetraethylammonium (TEA) of the membrane water channel aqu...

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Detalhes bibliográficos
Main Authors: Müller, E. Matthias, Hub, Jochen S., Grubmüller, Helmut, de Groot, Bert L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756347/
https://ncbi.nlm.nih.gov/pubmed/18196268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-007-0422-0
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