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DeltaNp63 overexpression, alone and in combination with other biomarkers, predicts the development of oral cancer in patients with leukoplakia

PURPOSE: The risk of malignant transformation of oral preneoplastic lesion (OPL) is difficult to assess. DeltaNp63 is an early oncoprotein associated with mucosal tumorigenesis. The purpose of this study was to assess deltaNp63 expression in OPL and its role as a marker of oral cancer risk. EXPERIME...

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Main Authors: Saintigny, Pierre, El-Naggar, Adel K., Papadimitrakopoulou, Vali, Ren, Hening, Fan, You-Hong, Feng, Lei, Lee, J. Jack, Kim, Edward S., Hong, Waun Ki, Lippman, Scott M., Mao, Li
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756317/
https://ncbi.nlm.nih.gov/pubmed/19773378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0498
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