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Schistosoma mansoni arginase shares functional similarities with human orthologs but depends upon disulphide bridges for enzymatic activity

Schistosome helminths constitute a major health risk for the human population in many tropical areas. We demonstrate for the first time that several developmental stages of the human parasite Schistosoma mansoni express arginase, which is responsible for the hydrolysis of l-arginine to l-ornithine a...

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Detalhes bibliográficos
Main Authors: Fitzpatrick, Jennifer M., Fuentes, Jose M., Chalmers, Iain W., Wynn, Thomas A., Modolell, Manuel, Hoffmann, Karl F., Hesse, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756234/
https://ncbi.nlm.nih.gov/pubmed/18723022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpara.2008.06.015
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